Gastric Perforation due to Mucormycosis in a Patient with Diabetic Ketoacidosis and Chronic Pancreatitis

ABSTRACT

Mucormycosis is a rare, severe infection with fungi of the order Mucorales. It is usually found in immunocompromised patients with diabetic ketoacidosis, glucocorticosteroid use, neutropenia in the setting of malignancy, and burns. Rhinocerebral disease is the most common form of mucormycosis. Other major symptoms are pulmonary, cutaneous, gastrointestinal, and systemic dissemination. Successful treatment requires removal of the underlying risk factor, antifungal therapy with amphotericin B, and aggressive surgery. We present a case of gastric perforation due to mucormycosis with diabetic ketoacidosis and chronic pancreatitis, with a review of the literature.