Gastrointestinal Stromal Tumor Accompanied with von Recklinghausen's Disease: Positive for CD117, CD34, SMA and S-100 Protein
Journal of the Korean Surgical Society
;
: 65-69, 2006.
Artigo
em Coreano
| WPRIM
| ID: wpr-176003
ABSTRACT
Gastrointestinal stromal tumors (GISTs) are CD117-positive primary mesenchymal tumors of the gastrointestinal tract and they have a characteristic set of morphologic features. GISTs have been noted to have a possible non-random association with neurofibromatosis-1 (NF-1, von Recklinghausen disease). We report here on a case of multiple GISTs with abundant skenoid fiber in the jejunum of a 47-year-old woman, and this condition was accompanied with NF-1. The tumor cells coexpressed smooth muscle actin, S-100 protein, CD117 and CD34. These immunohistochemical results are extremely rare findings for GISTs accompanying with NF-1. We think this is the first report of GISTs arising within NF-1 with the dual immunohistochemical differentiation of neuronal and muscular markers.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Proteínas S100
/
Actinas
/
Neurofibromatose 1
/
Neurofibromatoses
/
Trato Gastrointestinal
/
Tumores do Estroma Gastrointestinal
/
Jejuno
/
Músculo Liso
/
Neurônios
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Surgical Society
Ano de publicação:
2006
Tipo de documento:
Artigo
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