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Comparison of survival rates between patients treated with conventional radiotherapy and helical tomotherapy for head and neck cancer
Radiation Oncology Journal ; : 1-11, 2013.
Artigo em Inglês | WPRIM | ID: wpr-17612
ABSTRACT

PURPOSE:

Compared to conventional radiotherapy (RT), intensity-modulated radiotherapy (IMRT) significantly reduces the rate of treatment-induced late toxicities in head and neck cancer. However, a clear survival benefit of IMRT over conventional RT has not yet been shown. This study is among the first comparative study to compare the survival rates between conventional RT and helical tomotherapy in head and neck cancer. MATERIALS AND

METHODS:

From January 2008 to November 2011, 37 patients received conventional RT and 30 patients received helical tomotherapy for management of head and neck cancer. We retrospectively compared the survival rates between patients treated with conventional RT and helical tomotherapy, and analyzed the prognostic factors for survival.

RESULTS:

The 1- and 2-year locoregional recurrence-free survival rates were 61.2% and 58.1% for the conventional RT group, 89.3% and 80.3% for the helical tomotherapy group, respectively. The locoregional recurrence-free survival rates of the helical tomotherapy group were significantly higher than conventional RT group (p = 0.029). There were no significant differences in the overall and distant metastasis-free survival between the two groups. RT technique, tumor stage, and RT duration were significant prognostic factors for locoregional recurrence-free survival.

CONCLUSION:

This study showed the locoregional recurrence-free survival benefits of helical tomotherapy in the treatment of head and neck cancers.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Taxa de Sobrevida / Estudos Retrospectivos / Radioterapia de Intensidade Modulada / Cabeça / Neoplasias de Cabeça e Pescoço / Pescoço Tipo de estudo: Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: Radiation Oncology Journal Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Taxa de Sobrevida / Estudos Retrospectivos / Radioterapia de Intensidade Modulada / Cabeça / Neoplasias de Cabeça e Pescoço / Pescoço Tipo de estudo: Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: Radiation Oncology Journal Ano de publicação: 2013 Tipo de documento: Artigo