Impact of serum C-reactive protein level on the prognosis of patients with hepatocellular carcinoma undergoing TACE
Clinical and Molecular Hepatology
;
: 70-77, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-176454
ABSTRACT
BACKGROUND/AIMS:
The aim of this study was to determine the relationship between serum CRP levels and the prognosis of hepatocellular carcinoma (HCC) patients.METHODS:
HCC patients who underwent the first session of transcatheter arterial chemoembolization (TACE) between January 2005 and December 2009 (n=211) were analyzed retrospectively. The patients were divided into two groups high C-reactive protein (CRP; > or =1 mg/dL, n=51) and low CRP ( or =5 cm. In addition, subgroup analysis of matched CRP according to TNM stage revealed that elevated serum CRP was independently associated with tumor type, WBC count, and tumorprogression-free survival.CONCLUSIONS:
A high serum CRP level is associated with large tumors and a poorly defined tumor type, and is significantly associated with 10-month mortality in patients with large HCC (size > or =5 cm) who undergo TACE.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Índice de Gravidade de Doença
/
Proteína C-Reativa
/
Modelos de Riscos Proporcionais
/
Análise Multivariada
/
Estudos Retrospectivos
/
Fatores de Risco
/
Quimioembolização Terapêutica
/
Carcinoma Hepatocelular
/
Intervalo Livre de Doença
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2013
Tipo de documento:
Artigo
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