A Patient with Coexisting Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome
Journal of Clinical Neurology
;
: 235-237, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-177468
ABSTRACT
BACKGROUND:
The coexistence of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) is very rare and remains controversial. CASE REPORT A 48-year-old woman initially presented with noticeable right ptosis and intermittent diplopia. She then developed fluctuating proximal limb weakness and difficulty in swallowing. The serum titer of anti-acetylcholine-receptor antibody was elevated and the edrophonium (Tensilon) test was positive. However, repetitive nerve stimulation revealed abnormalities typical of LEMS. The patient exhibited a good response to treatment with anticholinesterase inhibitors and steroids, and long-term evaluation disclosed that she presented with the clinical, electrophysiological, and immunological characteristics of both diseases.CONCLUSIONS:
The reported clinical and electrophysiological features suggest that this patient was a very rare case of combined MG and LEMS.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esteroides
/
Síndrome Miastênica de Lambert-Eaton
/
Deglutição
/
Diplopia
/
Edrofônio
/
Extremidades
/
Miastenia Gravis
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Clinical Neurology
Ano de publicação:
2012
Tipo de documento:
Artigo
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