Serum biomarkers for predicting pregnancy outcome in women undergoing IVF: human chorionic gonadotropin, progesterone, and inhibin A level at 11 days post-ET / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
;
: 28-32, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-17760
ABSTRACT
OBJECTIVE:
This study was performed to assess the prognostic value of serum hCG, progesterone, and inhibin A levels measured at 11 days post-ET for predicting pregnancy outcome in women participating in IVF.METHODS:
Between May 2005 and April 2008, sera were obtained from 70 infertile women who underwent IVF-ET at 11 days post-ET and stored. HCG, progesterone, and inhibin A levels were measured by commercial enzyme-linked immunosorbent assay kits. The predictive accuracy of hCG, progesterone, and inhibin A levels for establishment of intrauterine pregnancy and ongoing pregnancy was calculated by receiver-operating characteristic curve analysis.RESULTS:
For the prediction of intrauterine and ongoing pregnancy, serum hCG was better than progesterone and inhibin A. The predictive performance of progesterone and inhibin A was similar. The serum progesterone and inhibin A levels were significantly correlated each other (r=0.915, p=0.010).CONCLUSION:
A single measurement of the serum hCG level is sufficient to predict pregnancy outcome in IVF-ET patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Progesterona
/
Ensaio de Imunoadsorção Enzimática
/
Resultado da Gravidez
/
Biomarcadores
/
Fertilização in vitro
/
Transferência Embrionária
/
Gonadotropina Coriônica
/
Inibinas
Tipo de estudo:
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Clinical and Experimental Reproductive Medicine
Ano de publicação:
2012
Tipo de documento:
Artigo
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