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A Case of Miliary Brain Metastasis of Lung Cancer Mimicking Neurocysticercosis / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases ; : 182-186, 2012.
Artigo em Coreano | WPRIM | ID: wpr-177717
ABSTRACT
Miliary brain metastasis from the lung is uncommon and has a poor therapeutic response. We report a case of pulmonary adenocarcinoma combined with multiple brain cystic lesions that were initially misdiagnosed as neurocysticercosis. A 53-year-old male who never smoked was admitted to our hospital with complaints of agitation and cognitive impairment. Brain magnetic resonance imaging showed innumerable, small nodular lesions with a central, low signal intensity in whole brain parenchyma. His symptoms were not improved by the empirical praziquantel medication for disseminated neurocysticercosis. After a transbronchial biopsy from the right middle lobe, we could diagnose the primary lung adenocarcinoma with a single nucleotide polymorphism in the epidermal growth factor receptor exon 20 at codon 787 (Q787Q). His neurologic symptoms and imaging findings have been gradually improving with a first-line Gefitinib treatment for five months. We recommend a more active diagnostic approach including biopsy in case of atypical imaging findings.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Praziquantel / Quinazolinas / Fumaça / Biópsia / Encéfalo / Códon / Imageamento por Ressonância Magnética / Adenocarcinoma / Éxons / Neurocisticercose Limite: Humanos / Masculino Idioma: Coreano Revista: Tuberculosis and Respiratory Diseases Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Praziquantel / Quinazolinas / Fumaça / Biópsia / Encéfalo / Códon / Imageamento por Ressonância Magnética / Adenocarcinoma / Éxons / Neurocisticercose Limite: Humanos / Masculino Idioma: Coreano Revista: Tuberculosis and Respiratory Diseases Ano de publicação: 2012 Tipo de documento: Artigo