A Clinical and Pathological Study of Sarcoidosis / 대한피부과학회지

ABSTRACT

BACKGROUND: The occurane of sarcoidosis seems to be increased recently. A proportion of patients initiallly visit the derrnatological department. However, there are few clinical reports about sarcoidosis for the dermatolagist. OBJECTIVE: This study wa performed to find the clinical and histopathological characteristis of sarcoidosis as a multisystemic disease. METHODS: We reviwed the chart of patients with sarcoidosis who were diagnosed at SNUH from 1984 to 1994 and analysed the characteristics of the clinical and histopathologic findings according to several factors. RESULTS: 1)Man to woman ratio was 1 2 and 70% of patients were in theirs third to fifth decades. 2)The main complaints were respiratory symtoms and cutaneous lesion. 3)The most frequently invloved organ was intrathoracic, followed by skin, peripheral lymph node, eye and bone in that order. 4)The cutaneous lesion was found in 50% of patients(15 out of 30) and specitic lesions were present in 14 cases. A subcitaneous nodule was the most common lesion(67%). 5)In subcutaenous sarcoicosis, there was hilar lymphadenopathy in 70% of the patients, lung parenchymal infiltration in 10%, peripheral lymphadenopathy in 30%, bony lesion in 30%. 6)The laboratory and histopathological findings were similar to previously reported results. CONCLUSION: The general features of patients were similar to other reports except for the fre quency of cutaneous involviment. Cutaneous involvement was found in 50% of patients and this was higher than in foreigr reports. In cutaneous sarcoidosis, the subcutaneous nodule was the most frequent specific lesior.