Refractory rickets caused by mild distal renal tubular acidosis
Annals of Pediatric Endocrinology & Metabolism
;
: 152-155, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-178351
ABSTRACT
Type I (distal) renal tubular acidosis (RTA) is a disorder associated with the failure to excrete hydrogen ions from the distal renal tubule. It is characterized by hyperchloremic metabolic acidosis, an abnormal increase in urine pH, reduced urinary excretion of ammonium and bicarbonate ions, and mild deterioration in renal function. Hypercalciuria is common in distal RTA because of bone resorption, which increases as a buffer against metabolic acidosis. This can result in intractable rickets. We describe a case of distal RTA with nephrocalcinosis during follow-up of rickets in a patient who presented with clinical manifestations of short stature, failure to thrive, recurrent vomiting, dehydration, and irritability.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prótons
/
Raquitismo
/
Acidose
/
Acidose Tubular Renal
/
Vômito
/
Bicarbonatos
/
Reabsorção Óssea
/
Seguimentos
/
Desidratação
/
Hipercalciúria
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Annals of Pediatric Endocrinology & Metabolism
Ano de publicação:
2013
Tipo de documento:
Artigo
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