Four Cases of Majocchi's granuloma / 대한의진균학회지

ABSTRACT

Dermatophytes usually do not invade beyond the epidermis. However mechanical breakage of the skin resulting from scratching or trauma and immunocompromised state, such as diabetes mellitus, lymphoma, and long-term steroid use may allow penetration of the fungi into reticular dermis. Cutaneous granulomas produced by infection with superficial fungi are infrequently recognized. We report four cases of dermatophytic granuloma on the lower extremities. Histopathologic examinations of the skin lesions of four patients showed chronic granulomatous inflammation with fungal elements. Cultures of Sabouraud's media with excised tissue revealed Trichophyton(T.) rubrum in two patients and T. mentagrophytes in one patient. The patients were treated with oral administration of terbinafine or itraconazole for 2-4 weeks.