Short-Term Effect of High Dose of Vitamin C on Coronary Flow Velocity and Coronary Flow Reserve in Healthy Young Non-Smoker Men
Journal of the Korean Society of Echocardiography
; : 78-82, 2004.
Article
em Ko
| WPRIM
| ID: wpr-179215
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND AND OBJECTIVES: Vitamin C, water-soluble antioxidant, has been reported to restore coronary microcirculatory responsiveness and impaired coronary flow reserve in smokers. However, the effect of high dose of vitamin C on coronary circulation is unclear in nonsmokers. METHODS: We used transthoracic echocardiography to measure the coronary flow reserve, an integrated measure of coronary flow in 20 male healthy nonsmokers (26+/-3 years) before and after administration of the high dose of vitamin C. RESULTS: The coronary peak diastolic velocity was increased by 14.8% after administration of antioxidant vitamin C, whereas the coronary flow reserve did not changed. CONCLUSION: High dose of vitamin C acutely increases the coronary flow velocity without restoration of coronary flow reserve in male healthy nonsmokers.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Ácido Ascórbico
/
Vitaminas
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Ecocardiografia
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Circulação Coronária
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Lobelina
Limite:
Humans
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Male
Idioma:
Ko
Revista:
Journal of the Korean Society of Echocardiography
Ano de publicação:
2004
Tipo de documento:
Article