Establishment of a Korea HPV cohort study / 부인종양
Journal of Gynecologic Oncology
;
: 59-65, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-179220
ABSTRACT
We have designed a five-year multicentre prospective cohort study in women who are both human papillomavirus (HPV)-positive with either atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL) of cervix. This study aimed to analyze the risk of developing a high-grade squamous intraepithelial lesion (HSIL) from either ASCUS or LSIL in HPV-positive women, so called 'progression' rate, to investigate differences in the progression rates according to HPV type-specific infection, and to evaluate the various factors associated with the persistence or clearance of HPV infection in the Korean population. At present, the study protocol composed of cervical cytology, HPV DNA testing, and questionnaire have been conducted actively since the first participant was enrolled in 2010. This study is the first nationwide Korea HPV cohort study. Our data will provide valuable information about not only the ambiguous cytology results of ASCUS and LSIL but also the effect of the specific HPV type and other various factors on the progression to HSIL. Finally, the results of our study will be helpful and applicable to determine the primary cervical cancer prevention strategies.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Displasia do Colo do Útero
/
Neoplasias do Colo do Útero
/
Colo do Útero
/
Inquéritos e Questionários
/
Estudos de Coortes
/
Testes de DNA para Papilomavírus Humano
/
Coreia (Geográfico)
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
Limite:
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of Gynecologic Oncology
Ano de publicação:
2013
Tipo de documento:
Artigo
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