A Case of Rh-incompatible Allogeneic Bone Marrow Transplantation: Transplant of E- and c-positive Bone Marrow in a Recipient with Anti-E and Anti-c Antibodies / 대한수혈학회지

ABSTRACT

The effects of Rh incompatibility in bone marrow transplantation (BMT) has not been studied extensively as ABO incompatibility. But it has been known that Rh incompatibility does not impair the engraftment of donor bone marrow. The recipient's blood groups were AB, DCe, who has anti-E and anti-c in her serum. The sibling donor blood groups were B, DCEce. There was a minor ABO incompatibility and Rh incompatibility due to anti-E and anti-c between donor and recipient. We performed the plasma and RBC depletion of marrow using the cell separator before it was infused. The clinical course after BMT was not eventful except mild delayed hemolysis and delayed hematopoietic recovery, which may be attributable to low marrow cell dose.