Genetic Signatures of Asthma Exacerbation
Allergy, Asthma & Immunology Research
;
: 191-199, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-179289
ABSTRACT
Asthma exacerbation (AE) usually denotes worsening of asthma symptoms that requires intense management to prevent further deterioration. AE has been reported to correlate with clinical and demographic factors, such as race, gender, and treatment compliance as well as environmental factors, such as viral infection, smoking, and air pollution. In addition, recent observations suggest that there are likely to be genetic factors specific to AE. Understanding genetic factors specific to AE is essential to develop therapy tailored for exacerbation-prone asthma. Here, we summarize the results of studies involving genetic risk factors for AE. To simplify and enhance understanding, we reviewed the studies according to the following categories hypothesis-driven approaches, hypothesis-free approaches, gene-environment interactions, and pharmacogenetics.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacogenética
/
Asma
/
Fumaça
/
Fumar
/
Demografia
/
Fatores de Risco
/
Complacência (Medida de Distensibilidade)
/
Grupos Raciais
/
Poluição do Ar
/
Estudo de Associação Genômica Ampla
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Allergy, Asthma & Immunology Research
Ano de publicação:
2017
Tipo de documento:
Artigo
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