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Development of IgA Nephropathy after Clinical Remission of Dense Deposit Disease / 대한신장학회지
Korean Journal of Nephrology ; : 125-130, 2010.
Artigo em Inglês | WPRIM | ID: wpr-179480
ABSTRACT
Dense deposit disease (DDD) is a rare primary glomerulonephritis characterized by continuous band- like intramembranous dense deposits detectable on electron microscopy. We describe a case of DDD with sequential mesangial proliferative glomerulonephritis, membranoproliferative glomerulonephritis, minor glomerular alterations, and a second round of mesangial proliferative glomerulonephritis during a 13-year period. Electron dense deposits were typical of DDD in the first and second biopsies taken one year apart. However, deposits dissolved and the glomerular cellularity and basement membrane normalized with clinical remission, which was achieved by a course of immunosuppressive therapy lasting seven years. The fourth biopsy was performed due to recurrence of microscopic hematuria and showed predominant mesangial IgA deposits without glomerular capillary alteration, which was interpreted as development of IgA nephropathy after remission of DDD or coexistence with nearly healed DDD in this patient.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Membrana Basal / Biópsia / Imunoglobulina A / Capilares / Microscopia Eletrônica / Glomerulonefrite Membranoproliferativa / Diclorodifenildicloroetano / Elétrons / Glomerulonefrite Idioma: Inglês Revista: Korean Journal of Nephrology Ano de publicação: 2010 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Membrana Basal / Biópsia / Imunoglobulina A / Capilares / Microscopia Eletrônica / Glomerulonefrite Membranoproliferativa / Diclorodifenildicloroetano / Elétrons / Glomerulonefrite Idioma: Inglês Revista: Korean Journal of Nephrology Ano de publicação: 2010 Tipo de documento: Artigo