Development of IgA Nephropathy after Clinical Remission of Dense Deposit Disease / 대한신장학회지
Korean Journal of Nephrology
;
: 125-130, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-179480
ABSTRACT
Dense deposit disease (DDD) is a rare primary glomerulonephritis characterized by continuous band- like intramembranous dense deposits detectable on electron microscopy. We describe a case of DDD with sequential mesangial proliferative glomerulonephritis, membranoproliferative glomerulonephritis, minor glomerular alterations, and a second round of mesangial proliferative glomerulonephritis during a 13-year period. Electron dense deposits were typical of DDD in the first and second biopsies taken one year apart. However, deposits dissolved and the glomerular cellularity and basement membrane normalized with clinical remission, which was achieved by a course of immunosuppressive therapy lasting seven years. The fourth biopsy was performed due to recurrence of microscopic hematuria and showed predominant mesangial IgA deposits without glomerular capillary alteration, which was interpreted as development of IgA nephropathy after remission of DDD or coexistence with nearly healed DDD in this patient.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Recidiva
/
Membrana Basal
/
Biópsia
/
Imunoglobulina A
/
Capilares
/
Microscopia Eletrônica
/
Glomerulonefrite Membranoproliferativa
/
Diclorodifenildicloroetano
/
Elétrons
/
Glomerulonefrite
Idioma:
Inglês
Revista:
Korean Journal of Nephrology
Ano de publicação:
2010
Tipo de documento:
Artigo
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