Your browser doesn't support javascript.
loading
Influence of Chronic Sinusitis and Nasal Polyp on the Lower Airway of Subjects Without Lower Airway Diseases
Allergy, Asthma & Immunology Research ; : 310-315, 2014.
Artigo em Inglês | WPRIM | ID: wpr-17984
ABSTRACT

PURPOSE:

Upper and lower respiratory tract pathologies are believed to be interrelated; however, the impact of upper airway inflammation on lung function in subjects without lung disease has not been evaluated. This study investigated the association of CT finding suggesting chronic sinusitis and lung function in healthy subjects without lung disease.

METHODS:

This was a retrospective study of prospectively collected data from 284 subjects who underwent a pulmonary function test, bronchial provocation test, rhinoscopy, and osteomeatal unit computed tomography offered as a private health check-up option.

RESULTS:

CT findings showed that the sinusitis group had a significantly lower FEV1/FVC ratio than subjects without sinusitis finding (78.62% vs 84.19%, P=0.019). Among the sinusitis group, subjects classified by CT findings as the extensive disease group had a slightly lower FEV1/FVC than those of the limited disease group (76.6% vs 79.5%, P=0.014) and the associations were independent of the presence of airway hyperresponsiveness. The subjects with nasal polyp had also lower FEV1 and FEV1/FVC than subjects without nasal polyp (FEV1 100.0% vs 103.6%, P=0.045, FEV1/FVC 77.4% vs 80.0%, P=0.005).

CONCLUSIONS:

CT findings suggesting chronic sinusitis and nasal polyp were associated with subclinical lower airway flow limitation even in the absence of underlying lung disease.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Testes de Função Respiratória / Sistema Respiratório / Sinusite / Testes de Provocação Brônquica / Pólipos Nasais / Estudos Prospectivos / Estudos Retrospectivos / Inflamação / Pulmão Tipo de estudo: Estudo observacional / Fatores de risco Idioma: Inglês Revista: Allergy, Asthma & Immunology Research Ano de publicação: 2014 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Testes de Função Respiratória / Sistema Respiratório / Sinusite / Testes de Provocação Brônquica / Pólipos Nasais / Estudos Prospectivos / Estudos Retrospectivos / Inflamação / Pulmão Tipo de estudo: Estudo observacional / Fatores de risco Idioma: Inglês Revista: Allergy, Asthma & Immunology Research Ano de publicação: 2014 Tipo de documento: Artigo