Long-Term Recurrence Rates of Peptic Ulcers without Helicobacter pylori
Gut and Liver
;
: 719-725, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-179857
ABSTRACT
BACKGROUND/AIMS:
The purpose of this study is to investigate the recurrence rate of peptic ulcer disease (PUD) over a long follow-up period with PUD patients without Helicobacter pylori.METHODS:
We retrospectively reviewed patients diagnosed with PUD on endoscopy and divided them into two groups a H. pylori-negative group (HP-negative group), and a group of patients with untreated H. pylori (HP noneradicated group). We compared the recurrence rates of PUD in these two groups and analyzed the factors that affected ulcer recurrence.RESULTS:
Total of nine hospitals in Korea participated, and a total of 1,761 patients were retrospectively reviewed. The HP-negative group included 553 patients, and the HP noneradicated group included 372 patients. The 5-year cumulative probabilities of PUD recurrence were 36.4% in the HP-negative group and 43.8% in the HP noneradicated group (p=0.113). The factors that were found to affect recurrence in the HP-negative group were elder, male, and comorbid chronic kidney disease.CONCLUSIONS:
The 5-year cumulative probability of PUD recurrence without H. pylori infection after a long-term follow-up was 36.4% and the factors that affected recurrence were elder, male, and comorbid chronic kidney disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera Péptica
/
Recidiva
/
Úlcera
/
Estudos Retrospectivos
/
Seguimentos
/
Helicobacter pylori
/
Helicobacter
/
Endoscopia
/
Insuficiência Renal Crônica
/
Coreia (Geográfico)
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Gut and Liver
Ano de publicação:
2016
Tipo de documento:
Artigo
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