Two Cases of Successful Treatment With Topiramate in Patients With Meniere's Disease With Migraine

ABSTRACT

OBJECTIVE: To investigate the effects of topiramate on vestibular symptoms in patients with Meniere's disease and migraine CASE REPORTS: We present two patients with Meniere's disease and migraine, who did not respond to the salt reduction diet and diuretics. Topiramate was given and maintained for several months. Frequency and severity of headache and vestibular symptoms decreased after initiation of the topiramate. CONCLUSIONS: Topiramate can be used satisfactorily for the patients with Meniere's disease and migraine, who are refractory to regular conservative treatment for Meniere's disease, when vertigo attacks are accompanied by migraine.