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Polymorphism and forensic efficiency of 5X-STR loci in Korean / 대한법의학회지
Korean Journal of Legal Medicine ; : 51-64, 2003.
Artigo em Coreano | WPRIM | ID: wpr-180558
ABSTRACT
This study intends to examine the polymorphism of 5 STR loci inX-chromosome (GATA172D05, HPRTB, DXS8377, DXS101, HumARA) and to evaluate usefulness of them in forensic identification. 100 unrelated Korean men and women were selected. DNA was extracted from these sample and PCR was performed to amplify it. And using automated DNA sequencer and computer program, the genotype and allele frequency of them were investigated and analyzed. The following results were obtained 1. The genetic analysis of 5 STR loci inX-chromosome was performed with quadruplex PCR for GATA172D05, HPRTB, DXS8377, HumARA and monoplex PCR for DXS101. 2. Polymorphism information content of 5 loci is higher than 0.5, the high information content is observed. The heterozygosity is higher in DXS8377, DXS101, HumARA than others. 3. The power of discrimination is revealed high in all 5 loci in women, but in men DXS8377 and HumARA is higher than others. 4. The mean exclusion chance is revealed high in DXS8377 and HumARA which have more alleles than others in trio case and motherless case. 5. The difference of allele frequency is observed with other population group in DXS8377, DXS101, HumARA of Korean population group. Based on the results of this study, the allele frequency and population data of 5 STR loci inX-chromosome may be useful in forensic investigation.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: DNA / Reação em Cadeia da Polimerase / Grupos Populacionais / Discriminação Psicológica / Alelos / Frequência do Gene / Genótipo Limite: Feminino / Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Legal Medicine Ano de publicação: 2003 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: DNA / Reação em Cadeia da Polimerase / Grupos Populacionais / Discriminação Psicológica / Alelos / Frequência do Gene / Genótipo Limite: Feminino / Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Legal Medicine Ano de publicação: 2003 Tipo de documento: Artigo