Biomarkers of Sepsis / 감염과화학요법
Infection and Chemotherapy
; : 1-12, 2014.
Article
em En
| WPRIM
| ID: wpr-180767
Biblioteca responsável:
WPRO
ABSTRACT
Sepsis remains a leading cause of death in critically ill patients, despite efforts to improve patient outcome. Thus far, no magic drugs exist for severe sepsis and septic shock. Instead, early diagnosis and prompt initial management such as early goal-directed therapy are key to improve sepsis outcome. For early detection of sepsis, biological markers (biomarkers) can help clinicians to distinguish infection from host response to inflammation. Ideally, biomarkers can be used for risk stratification, diagnosis, monitoring of treatment responses, and outcome prediction. More than 170 biomarkers have been identified as useful for evaluating sepsis, including C-reactive protein, procalcitonin, various cytokines, and cell surface markers. Recently, studies have reported on the usefulness of biomarker-guided antibiotic stewardships. However, the other side of these numerous biomarkers is that no novel single laboratory marker can diagnose, predict, and track the treatment of sepsis. The purpose of this review is to summarize several key biomarkers from recent sepsis studies.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Prognóstico
/
Choque Séptico
/
Proteína C-Reativa
/
Biomarcadores
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Causas de Morte
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Citocinas
/
Estado Terminal
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Sepse
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Diagnóstico Precoce
/
Diagnóstico
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Infection and Chemotherapy
Ano de publicação:
2014
Tipo de documento:
Article