Ischemia-modified albumin (IMA) is not useful for detecting myocardial ischemia during symptom-limited exercise stress tests
The Korean Journal of Internal Medicine
;
: 121-126, 2008.
Artigo
em Inglês
| WPRIM
| ID: wpr-181617
ABSTRACT
BACKGROUND/AIMS:
We examined the ischemia-modified albumin (IMA) level during exercise in patients with coronary artery disease (CAD).METHODS:
Forty patients with a history of chest pain underwent both symptom-limited treadmill exercise stress testing and coronary angiography within one week. During the treadmill tests, blood samples were obtained at baseline and 5 min after exercise to measure the serum IMA level.RESULTS:
Of the 40 patients, fourteen (35%, CAD group) had significant coronary artery stenosis, while the other 26 (65%, non-CAD group) did not. The baseline and post-exercise IMA levels in the two groups did not differ significantly (105.2+/-7.2 vs. 107.7+/-6.7 U/mL at baseline and 93.1+/-10.1 vs. 94.8+/-5.7 U/mL at post-exercise in the CAD and non-CAD groups, p=0.29 and 0.57, respectively). The changes in IMA after exercise did not differ either (-10.4+/-7.5 vs. -14.0+/-7.6 U/mL in the CAD and non-CAD groups, respectively, p=0.10). Similarly, the change in IMA between the exercise ECG test positive (TMT positive, n=9) and negative (TMT negative, n=20) groups did not differ (-14.63+/-5.19, vs -8.50+/-9.01 U/mL, p=0.15, in the TMT positive and negative groups, respectively).CONCLUSIONS:
Our results suggest that IMA has limitation in detecting myocardial ischemia during symptom-limited exercise stress tests.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dor no Peito
/
Projetos Piloto
/
Isquemia Miocárdica
/
Ácido Láctico
/
Albuminas
/
Eletrocardiografia
/
Teste de Esforço
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo
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