Your browser doesn't support javascript.
loading
Larger Testicular Volume Is Independently Associated with Favorable Indices of Lung Function / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases ; : 385-391, 2017.
Artigo em Inglês | WPRIM | ID: wpr-182299
ABSTRACT

BACKGROUND:

Men with chronic obstructive pulmonary disease, have reduced endogenous testosterone levels, but the relationship between pulmonary function and endogenous testosterone levels, is inconsistent. Testicular volume is a known indicator of endogenous testosterone levels, male fertility, and male potency. In the present study, the authors investigated the relationship, between testicular volume and lung function.

METHODS:

One hundred and eighty-one South Korean men age 40-70, hospitalized for urological surgery, were retrospectively enrolled, irrespective of the presence of respiratory disease. Study subjects underwent pulmonary function testing, prior to procedures, and testicular volumes were measured by orchidometry. Testosterone levels of patients in blood samples collected between 7 AM and 11 AM, were measured by a direct chemiluminescent immunoassay.

RESULTS:

The 181 study subjects were divided into two groups, by testicular volume (≥35 mL vs. <35 mL), the larger testes group, had better lung functions (forced vital capacity [FVC] 3.87±0.65 L vs. 3.66±0.65 L, p=0.037; forced expiratory volume in 1 second [FEV1] 2.92±0.57 L vs. 2.65±0.61 L, p=0.002; FVC % predicted 98.2±15.2% vs. 93.8±13.1%, p=0.040; FEV1 % predicted 105.4±19.5% vs. 95.9±21.2%, p=0.002). In addition, the proportion of patients with a FEV1/FVC of <70%, was lower in the larger testes group. Univariate analysis conducted using linear regression models, revealed that testicular volume was correlated with FVC (r=0.162, p=0.029), FEV1 (r=0.218, p=0.003), FEV1/FVC (r=0.149, p=0.046), and FEV1 % predicted (r=0.178, p=0.017), and multivariate analysis using linear regression models, revealed that testicular volume was a significant predictive factor for FEV1 % predicted (β=0.159, p=0.041).

CONCLUSION:

Larger testicular volume was independently associated, with favorable indices of lung function. These results suggest that androgens, may contribute to better lung function.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Testes de Função Respiratória / Fenômenos Fisiológicos Respiratórios / Testículo / Testosterona / Imunoensaio / Modelos Lineares / Capacidade Vital / Volume Expiratório Forçado / Análise Multivariada / Estudos Retrospectivos Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos / Masculino Idioma: Inglês Revista: Tuberculosis and Respiratory Diseases Ano de publicação: 2017 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Testes de Função Respiratória / Fenômenos Fisiológicos Respiratórios / Testículo / Testosterona / Imunoensaio / Modelos Lineares / Capacidade Vital / Volume Expiratório Forçado / Análise Multivariada / Estudos Retrospectivos Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos / Masculino Idioma: Inglês Revista: Tuberculosis and Respiratory Diseases Ano de publicação: 2017 Tipo de documento: Artigo