Extensive Cornifying Darier's Disease without a Family History / 대한피부과학회지

ABSTRACT

Darier's disease is an uncommon inheritable genodermatosis that is characterized by recurrent waxy, hyperkeratotic papules that usually occur over the seborrheic areas. The characteristic histopathological changes are acantholysis leading to the formation of lacunae and dyskeratosis with corps ronds and grain, which are diagnostic clues of the disease along with the typical clinical features. A 50-year-old Korean male patient presented with an extensive involvement of whitish thick hyperkeratotic fissures, verrucoid plaques with oozing and foul odor over the skin for about 30 years. We report here on an unusual case of extensive cornifying Darier's disease in a patient who has no family history of this disease.