A case of desmoplastic small round cell tumor with Down's syndrome / 대한내과학회지
Korean Journal of Medicine
;
: 471-475, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-183150
ABSTRACT
A desmoplastic small round cell tumor (DSRCT) is a rare, aggressive neoplasm that occurs predominantly in children and young men. It presents as a large mass inside the abdomen, particularly within the pelvis, and may be accompanied by extensive tumor implants throughout the peritoneum. Microscopically, it typically appears as nests of small undifferentiated cells within a desmoplastic stroma. A DSRCT shows a special immunohistochemical staining pattern, expressing epithelial, neural, and muscle markers. A DSRCT is associated with a specific chromosomal translocation, t (11;22) (p13;q12), resulting in a chimeric EWS/WT1 transcript that is helpful for diagnosing this tumor. We experienced a case of DSRCT in a 19-year-old man who had been diagnosed with Down's syndrome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pelve
/
Peritônio
/
Translocação Genética
/
Síndrome de Down
/
Abdome
/
Tumor Desmoplásico de Pequenas Células Redondas
/
Músculos
Limite:
Criança
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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