Allopurinol-induced DRESS syndrome mimicking biliary obstruction
Clinical and Molecular Hepatology
;
: 71-75, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-18373
ABSTRACT
An 84-year-old man was admitted to our hospital with fever, jaundice, and itching. He had been diagnosed previously with chronic renal failure and diabetes, and had been taking allopurinol medication for 2 months. A physical examination revealed that he had a fever (38.8degrees C), jaundice, and a generalized maculopapular rash. Azotemia, eosinophilia, atypical lymphocytosis, elevation of liver enzymes, and hyperbilirubinemia were detected by blood analysis. Magnetic resonance cholangiography revealed multiple cysts similar to choledochal cysts in the liver along the biliary tree. Obstructive jaundice was suspected clinically, and so an endoscopic ultrasound examination was performed, which ruled out a diagnosis of obstructive jaundice. The patient was diagnosed with DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome due to allopurinol. Allopurinol treatment was stopped and steroid treatment was started. The patient died from cardiac arrest on day 15 following admission.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sistema Biliar
/
Bilirrubina
/
Doenças Biliares
/
Tomografia Computadorizada por Raios X
/
Alopurinol
/
Angiografia por Ressonância Magnética
/
Endossonografia
/
Creatina
/
Eosinófilos
/
Síndrome de Hipersensibilidade a Medicamentos
Limite:
Idoso
/
Aged80
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2014
Tipo de documento:
Artigo
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