Meconium Obstruction Syndrome in Two Extremely Low Birth Weight Infants

ABSTRACT

Ileal obstruction by meconium in premature and low birth weight infants is an unique clinical entity, and it is differentiated from other types of meconium obstruction not associated with cystic fibrosis. Markedly premature infants may present with intestinal obstruction symptoms resembling those of necrotizing enterocolitis, and perforation secondary to inspissated meconium. Between 2001 and 2006, two extremely low birth weight infants were treated for intestinal obstruction secondary to inspissated meconium. They were successfully treated with gastrografin enemas. Prompt diagnosis and appropriate management resulted in a beneficial patient outcome.