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Important predictor of mortality in patients with end-stage liver disease
Clinical and Molecular Hepatology ; : 105-115, 2013.
Artigo em Inglês | WPRIM | ID: wpr-186811
ABSTRACT
Prognosis is an essential part of the baseline assessment of any disease. For predicting prognosis of end-stage liver disease, many prognostic models were proposed. Child-Pugh score has been the reference for assessing the prognosis of cirrhosis for about three decades in end-stage liver disease. Despite of several limitations, recent large systematic review showed that Child-Pugh score was still robust predictors and it's components (bilirubin, albumin and prothrombin time) were followed by Child-Pugh score. Recently, Model for end-stage liver disease (MELD) score emerged as a "modern" alternative to Child-Pugh score. The MELD score has been an important role to accurately predict the severity of liver disease and effectively assess the risk of mortality. Due to several weakness of MELD score, new modified MELD scores (MELD-Na, Delta MELD) have been developed and validated. This review summarizes the current knowledge about the prognostic factors in end-stage liver disease, focusing on the role of Child-Pugh and MELD score.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Bilirrubina / Índice de Gravidade de Doença / Taxa de Sobrevida / Coeficiente Internacional Normatizado / Creatinina / Doença Hepática Terminal Tipo de estudo: Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: Clinical and Molecular Hepatology Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Bilirrubina / Índice de Gravidade de Doença / Taxa de Sobrevida / Coeficiente Internacional Normatizado / Creatinina / Doença Hepática Terminal Tipo de estudo: Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: Clinical and Molecular Hepatology Ano de publicação: 2013 Tipo de documento: Artigo