Cytomegalovirus Ventriculoencephalitis after Unrelated Double Cord Blood Stem Cell Transplantation with an Alemtuzumab-containing Preparative Regimen for Philadelphia-positive Acute Lymphoblastic Leukemia
Journal of Korean Medical Science
;
: 630-633, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-188010
ABSTRACT
Despite the prophylaxis and preemptive strategies using potent antiviral agents, cytomegalovirus (CMV) remains a major infectious cause of morbidity and mortality in allogeneic stem cell transplantation (SCT) recipients. Delayed immune reconstitution after SCT, such as cord blood and T-cell depleted SCT with the use of alemtuzumab, has been associated with an increased frequency of CMV disease as well as CMV reactivation. CMV disease involving central nervous system is an unusual presentation in the setting of SCT. We report a case of CMV ventriculoencephalitis after unrelated double cord blood SCT with an alemtuzumab-containing preparative regimen for Philadelphia-positive acute lymphoblastic leukemia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Evolução Fatal
/
Infecções por Citomegalovirus
/
Condicionamento Pré-Transplante
/
Citomegalovirus
/
Transplante de Células-Tronco de Sangue do Cordão Umbilical
/
Encefalite
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Anticorpos Monoclonais Humanizados
/
Anticorpos Monoclonais
/
Anticorpos Antineoplásicos
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2010
Tipo de documento:
Artigo
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