Your browser doesn't support javascript.
loading
A monoclonal antibody to cell surface antigen of human thymic epithelial cell
Journal of Korean Medical Science ; : 47-51, 1994.
Artigo em Inglês | WPRIM | ID: wpr-189271
ABSTRACT
The cell surface molecule identified by a monoclonal antibody(TE-1) to human thymic epithelial cell showed the specificity for thymic epithelial cells of both the cortex and medulla. TE-1 reacted with the epithelial cells of normal thymus and thymoma in fresh frozen tissues. The antigen recognized by TE-1 was mostly confined to the cell surface membrane and arranged in reticular network with long processes between thymocytes. On immunohistochemical analysis, TE-1 did not recognize normal epithelial cells of the uterine cervix, skin and stomach, and neoplastic cells of squamous cell carcinoma and gastric adenocarcinoma, all of which were stained with anti-cytokeratin monoclonal antibody. Among the tumor cell lines tested with flow cytometry, most of epithelial and all of hematopoietic cell origin were not labeled with TE-1. In summary, TE-1 appears to be a monoclonal antibody against a surface antigen of human thymic epithelial cell that is immunohistologically different from known epithelial cell surface antigens reported so far.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Timoma / Timo / Neoplasias do Timo / Isotipos de Imunoglobulinas / Imunoglobulina G / Células Tumorais Cultivadas / Imunofluorescência / Técnicas Imunoenzimáticas / Epitélio / Camundongos Endogâmicos BALB C Limite: Animais / Humanos Idioma: Inglês Revista: Journal of Korean Medical Science Ano de publicação: 1994 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Timoma / Timo / Neoplasias do Timo / Isotipos de Imunoglobulinas / Imunoglobulina G / Células Tumorais Cultivadas / Imunofluorescência / Técnicas Imunoenzimáticas / Epitélio / Camundongos Endogâmicos BALB C Limite: Animais / Humanos Idioma: Inglês Revista: Journal of Korean Medical Science Ano de publicação: 1994 Tipo de documento: Artigo