Evolutionary Signature of Information Transfer Complexity in Cellular Membrane Proteomes
Genomics & Informatics
;
: 111-121, 2009.
Artigo
em Inglês
| WPRIM
| ID: wpr-190148
ABSTRACT
Cell membrane proteins play crucial roles in the cell's molecular interaction with its environment and within itself. They consist of membrane-bound proteins and many types of transmembrane (TM) proteins such as receptors, transporters, channel proteins, and enzymes. Membrane proteomes of cellular organisms reveal some characteristics in their global topological distribution according to their evolutionary positions, and show their own information transfer complexity. Predicted transmembrane segments (TMSs) in membrane proteomes with HMMTOP showed near power-law distribution and frequency characteristics in 6-TMS and 7-TMS proteins in prokaryotes and eukaryotes, respectively. This reaffirms the important roles of membrane receptors in cellular communication and biological evolutionary history.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transdução de Sinais
/
Proteínas
/
Proteoma
/
Eucariotos
/
Proteínas de Membrana
/
Membranas
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Genomics & Informatics
Ano de publicação:
2009
Tipo de documento:
Artigo
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