Natural Killer Cell Activity in Rheumatoid Arthritis Measured by a Single Cell Cytotoxicity Assay
Yonsei Medical Journal
;
: 160-165, 1988.
Artigo
em Inglês
| WPRIM
| ID: wpr-190443
ABSTRACT
The natural killer(NK) cell activity of mononuclear cells (MNC) from peripheral blood (PB) and synovial fluid (SF) of 40 rheumatoid arthritis(RA) patients was investigated by employing 51-chromium-(51Cr) release microcytotoxicity and single cell cytotoxicity assays against K562 target cells. It has been revealed that SF-MNC from RA patients showed a significantly lower NK activity than PB-MNC from the same patients and this might be due to an impaired target binding capacity of the effector cells and not due to a deficiency of active NK cells.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artrite Reumatoide
/
Líquido Sinovial
/
Técnicas In Vitro
/
Testes Imunológicos de Citotoxicidade
/
Estudo Comparativo
/
Células Matadoras Naturais
/
Radioisótopos de Cromo
/
Citotoxicidade Imunológica
/
Pessoa de Meia-Idade
Limite:
Adolescente
/
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
1988
Tipo de documento:
Artigo
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