Alcohol Consumption as Risk Factor for Progression from Mild Cognitive Impairment to Dementia : A Clinical Research Center for Dementia of South Korea Study
Journal of Korean Geriatric Psychiatry
;
: 69-75, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-190689
ABSTRACT
OBJECTIVE:
Patients with mild cognitive impairment (MCI) are at high risk for dementia. Excessive alcohol consumption is known to adversely affect cognitive function. This study aimed to investigate the relationship between alcohol consumption and the risk for dementia in a cohort of MCI patients.METHODS:
Participants (n=416) with (MCI) who met Petersen's criteria were recruited from a nationwide, prospective cohort study of dementia and were followed for a median of 17.52 months (range 5.4-63.48). Alcohol consumption was evaluated at baseline.RESULTS:
One hundred twenty seven individuals (30.5%) developed incident dementia (115 Alzheimer disease) during follow-up. Patients with current alcohol consumption at baseline had a higher rate of progression to Alzheimer's dementia than those without current alcohol consumption (hazard ratio 1.61 ; 95% confidence interval 1.03 to 2.53).CONCLUSION:
Alcohol consumption may increase the risk of progression to Alzheimer's dementia in patients with MCI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Consumo de Bebidas Alcoólicas
/
Estudos Prospectivos
/
Fatores de Risco
/
Estudos de Coortes
/
Seguimentos
/
Demência
/
Doença de Alzheimer
/
Disfunção Cognitiva
/
Coreia (Geográfico)
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Journal of Korean Geriatric Psychiatry
Ano de publicação:
2014
Tipo de documento:
Artigo
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