Hemorrhagic gastroenteritis with Henoch-Sch?nlein purpura in adult / 대한내과학회지
Korean Journal of Medicine
;
: 628-637, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-191112
ABSTRACT
BACKGROUND:
To evaluate clinical manifestations, endoscopic findings and response to treatment in adult Henoch-Sch?nlein purpura (HSP) patients with hemorrhagic gastroenteritis.METHODS:
Twenty patients who were admitted to Kyungpook National University Hospital between 1996 and 2003 were included, based on the following criteria 1) diagnosed as HSP according to the criteria proposed by Michel et al., 2) older than 15 years old and 3) had evidences of gastrointestinal (GI) bleeding. Thirteen HSP patients who were older than 15 years old and had no evidences of GI bleeding were recruited as controls. We evaluated the clinical features and findings of upper GI endoscopy and colonoscopy.RESULTS:
Mean age and male to female ratio were not significantly different between patients with and without hemorrhagic gastroenteritis (age 29.5 +/- 15.1 vs. 30.5 +/- 13.5; MF=146 vs. 94, respectively). Patients with hemorrhagic gastroenteritis had a significantly higher frequency of petechiae on the upper extremities (p=0.015). In the multivariate analysis, petechial lesion on the upper extremities was a significant risk factor for hemorrhagic gastroenteritis (p=0.041). Mucosal lesions were found in 94.7% and 83.3% of patients on upper GI endoscopy and colonoscopy, showing that most patients (82.3%) had both upper and lower GI bleeding. Most patients with hemorrhagic gastroenteritis showed good response to high dose glucocorticoid therapy. Mortality and relapse rate were 10% and 5%, respectively.CONCLUSION:
In adult HSP patients, presence of petechiae on upper extremities may be a risk factor for hemorrhagic gastroenteritis. The present data suggest that both upper and lower GI examinations are necessary for proper evaluation of HSP patients with hemorrhagic gastroenteritis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Púrpura
/
Recidiva
/
Análise Multivariada
/
Fatores de Risco
/
Mortalidade
/
Colonoscopia
/
Extremidade Superior
/
Endoscopia
/
Gastroenterite
/
Hemorragia
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2005
Tipo de documento:
Artigo
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