A Case of Secondary Hemosiderosis and Hepatic Fibrosis in a Pateint with Acute Myelogenous Leukemia
Journal of the Korean Pediatric Society
;
: 420-424, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-191332
ABSTRACT
Chronic iron overload is associated with life-threatening complications, such as cardiomyopathy, liver cirrhosis, diabetes, hypothyroidism, hypoparathyroidism and hypogonadism. We experienced a case of secondary hemosiderosis with hepatic fibrosis in a 8-year-old boy who had been transfused 56 pints of packed red blood cells for a supportive therapy of acute myelogenous leukemia for a 27-month period. Intramuscular injection of Desferroxamine (40mg/kg/ day) was done for 9 months, however, there was no sign of improvement in hepatic size, consistency, and in liver biopsy findings. Except for mild thrmobocytopenia which seems to be the result of hypersplenism, the boy remained in remission for 3 2/3 years. We think, the prompt use of Desferroxamine therapy may be needed to avoid iron overload, if patients recieved multiple transfusions and high serum ferritin level.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biópsia
/
Transfusão de Sangue
/
Fibrose
/
Leucemia Mieloide Aguda
/
Sobrecarga de Ferro
/
Desferroxamina
/
Eritrócitos
/
Ferritinas
/
Hemossiderose
/
Hiperesplenismo
Limite:
Criança
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Pediatric Society
Ano de publicação:
1998
Tipo de documento:
Artigo
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