Tuberculous Meningitis in a Patient with Crohn's Disease, Which was Treated with Infliximab / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
; : 339-342, 2007.
Article
em Ko
| WPRIM
| ID: wpr-192073
Biblioteca responsável:
WPRO
ABSTRACT
Clinical trials of tumor necrosis factor (TNF) inhibitor have demonstrated significant efficacy in those patients with Crohn's disease that is not responsive to other anti-inflammatory drug. Infliximab is a human-murine chimeric monoclonal antibody with a high binding affinity and specificity for TNF-alpha. Yet therapy with infliximab is associated with an increased risk of opportunistic infection, and especially tuberculosis. Here we reported on a case of tuberculous meningitis in 26-year-old man, and he was treated with infliximab for uncontrolled and fistulous Crohn's disease. We also include a review of the literature.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Tuberculose
/
Tuberculose Meníngea
/
Infecções Oportunistas
/
Doença de Crohn
/
Sensibilidade e Especificidade
/
Fator de Necrose Tumoral alfa
/
Infliximab
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Gastrointestinal Endoscopy
Ano de publicação:
2007
Tipo de documento:
Article