NF-kappaB Activation in T Helper 17 Cell Differentiation
Immune Network
;
: 14-20, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-192389
ABSTRACT
CD28/T cell receptor ligation activates the NF-kappaB signaling cascade during CD4 T cell activation. NF-kappaB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently, many reports showed that NF-kappaB activation is also involved in T helper (Th) cell differentiation including Th17 cell differentiation. In this review, we discuss the current literature on NF-kappaB activation pathway and its effect on Th17 cell differentiation.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Receptores de Antígenos de Linfócitos T
/
Expressão Gênica
/
Diferenciação Celular
/
Sobrevivência Celular
/
NF-kappa B
/
Células Th17
/
Ligadura
Idioma:
Inglês
Revista:
Immune Network
Ano de publicação:
2014
Tipo de documento:
Artigo
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