The Clinical Characteristics and Predictive Factors of Stage IV Breast Cancer at the Initial Presentation: A Review of a Single Institute's Data / 한국유방암학회지
Journal of Breast Cancer
;
: 101-106, 2007.
Artigo
em Inglês
| WPRIM
| ID: wpr-192421
ABSTRACT
PURPOSE:
The aim of this study is to evaluate stage IV breast cancer at the initial presentation by the review of a single institute' data. We also tried to figure out the factors to predict stage IV breast cancer.METHODS:
We reviewed the prospectively collected database of 1,424 consecutive patients with primary breast cancer at the National Cancer Center in Korea from October 2000 to January 2005.RESULTS:
The proportion of stage IV breast cancer was 2.7% (38/1,424). The median tumor size of the stage IV patients was 4.1 cm. The most common metastatic site was bone (47.4%) followed by lung (44.7%) and liver (36.8%). Metastases were found in 0.9% (6/672) of the T1 tumors, 2.4% (13/535) of the T2 tumors, 8.3% (4/48) of the T3 tumors, and 27.1% (13/48) of the T4 tumors (p or =2 cm) (p=0.026), positive lymph node status (p104 IU/L) (p=0.013), aspartate transferase (>40 IU/L) (p=0.003) and CA15-3 (>32 U/mL) (p=0.025).CONCLUSION:
Our study showed that the factors to predict distant metastasis of breast cancer were large size of tumor, positive lymph node status, elevated alkaline phosphatase, aspartate transferase and CA15-3. Therefore breast cancer patients with those clinical characteristics should be carefully evaluated to detect distant metastasis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transferases
/
Mama
/
Neoplasias da Mama
/
Análise Multivariada
/
Estudos Prospectivos
/
Ácido Aspártico
/
Fosfatase Alcalina
/
Coreia (Geográfico)
/
Fígado
/
Pulmão
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of Breast Cancer
Ano de publicação:
2007
Tipo de documento:
Artigo
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