Association of Metabolic Factors and Prostate-Specific Antigen Levels with Prostate Volume in Medical Check-ups
Laboratory Medicine Online
;
: 212-217, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-192670
ABSTRACT
BACKGROUND:
Baseline prostate volume (PV) is related with the progression of benign prostatic hyperplasia (BPH). Although recent studies have reported the relationship between BPH and metabolic syndrome, the findings are inconsistent. Thus, this study was performed to investigate the association of PV with metabolic factors and prostate-specific antigen (PSA) in individuals with normal PV and clarify the factors associated with benign prostate enlargement (BPE), including PSA.METHODS:
We selected 3,915 health examinees aged >40 yr with a PSA level or =30 mL). We investigated the association of PV with metabolic factors and PSA using multiple linear regression analysis, and clarified the factors associated with BPE using logistic regression analysis.RESULTS:
The factors associated with PV were PSA, age, and waist circumference in individuals with normal PV. The factors associated with BPE were age, body mass index (BMI), and PSA. The logistic regression analysis adjusted for age and confounding factors showed that individuals with a BMI of 23-24.9 kg/m2, 25-29.9 kg/m2, and > or =30 kg/m2 had higher odds ratios of 1.580 (95% confidence interval, 1.171-2.131; P=0.003), 1.767 (1.332-2.344; P<0.001), and 2.024 (1.042-3.933; P=0.038), respectively, for BPE than individual with a BMI <23 kg/m2.CONCLUSIONS:
Abdominal obesity was significantly associated with PV in individuals with normal PV, whereas obesity was an associated metabolic factor of BPE. PSA level was positively associated with PV.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Próstata
/
Hiperplasia Prostática
/
Índice de Massa Corporal
/
Modelos Lineares
/
Modelos Logísticos
/
Razão de Chances
/
Ultrassonografia
/
Antígeno Prostático Específico
/
Circunferência da Cintura
/
Obesidade Abdominal
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Coreano
Revista:
Laboratory Medicine Online
Ano de publicação:
2014
Tipo de documento:
Artigo
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