Use of Splenectomy to Treat Evans Syndrome Following an ABO-Matched Liver Transplant / 대한내과학회지
Korean Journal of Medicine
;
: 464-468, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-194216
ABSTRACT
Evans syndrome is a rare complication that develops in adults after liver transplantation. The possible etiologies include ABO mismatch, viral infection, post-transplantation lymphoproliferative disease, graft-versus-host disease, and the use of certain immunosuppressive drugs (e.g., calcineurin inhibitors). Here, we present a case of Evans syndrome that developed after an ABO-matched liver transplant. Glucocorticosteroid, intravenous immunoglobulin, and alternative immunosuppressant therapies all failed. Weekly rituximab (375 mg/m2) was then administered for 4 weeks. The cytopenia improved transiently after the second dose of rituximab, but soon worsened again. However, the cytopenia normalized after a splenectomy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esplenectomia
/
Imunoglobulinas
/
Transplante de Fígado
/
Púrpura Trombocitopênica Idiopática
/
Calcineurina
/
Rituximab
/
Doença Enxerto-Hospedeiro
/
Anemia Hemolítica Autoimune
/
Fígado
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS