Animal Models of Traumatic Brain Injury
Brain & Neurorehabilitation
;
: 12-20, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-194252
ABSTRACT
Traumatic brain injury could be used to describe all injuries to the brain caused by external mechanical forces. It shows a variety of clinical manifestations from mild to severe forms and can result to death. Moderate to severe injuries can produce disabilities on physical, cognitive, behavioral, and emotional aspects. Animal models of traumatic brain injury have been developed to reproduce characteristics of human brain injury, to understand molecular and cellular pathophysiology and neurobehavioral outcomes following trauma and to find out the promising pharmacological drugs or rehabilitative skills to treat. This article reviewed the current experimental traumatic brain injury models, including weight drop, fluid percussion, and controlled cortical impact, and also the neurobehavioral assessments that are most commonly used to measure loss of function.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Percussão
/
Encéfalo
/
Lesões Encefálicas
/
Modelos Animais
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Brain & Neurorehabilitation
Ano de publicação:
2011
Tipo de documento:
Artigo
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