Reproductive and Hormonal Factors Associated with Fatty or Dense Breast Patterns among Korean Women / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 42-48, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-194258
ABSTRACT
PURPOSE:
Dense breasts have been suggested as a risk factor for breast cancer, but controversy still remains. This study evaluates the association of reproductive and hormonal factors with dense breasts among Korean women. MATERIALS ANDMETHODS:
Using a cross-sectional design, 516 women were recruited and classified for breast density patterns as being either fatty or dense, using the Breast Imaging Reporting and Data System (BI-RADS) of the American College of Radiology. Univariate and multivariate logistic regression models were used for statistical analysis.RESULTS:
In univariate logistic regression, older age, higher body mass index, older age at menarche, and oral contraceptive use were associated with more fatty breasts. On the contrary, longer duration of education, alcohol consumption, lower parity, menopause and use of hormone replacement therapy were associated with dense breasts. After adjustment, age and body mass index were inversely associated with breast density (p-value for trend or =2 children, nulliparous women had an 11.8-fold increase of dense breasts (p-value for trend <0.01). Compared to postmenopausal women, premenopausal women had 2.4-fold increase of dense breasts (odds ratio, 2.42; 95% confidence interval, 1.36 to 4.32).CONCLUSION:
Young age, lower body mass index, lower parity, and premenopausal status were significantly associated with dense breasts in Korea.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paridade
/
Mama
/
Neoplasias da Mama
/
Consumo de Bebidas Alcoólicas
/
Menarca
/
Menopausa
/
Sistemas de Informação
/
Mamografia
/
Índice de Massa Corporal
/
Modelos Logísticos
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Criança
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Cancer Research and Treatment
Ano de publicação:
2011
Tipo de documento:
Artigo
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