Clinical Predictors of Disease Progression in New-Onset Urticaria / 대한피부과학회지
Korean Journal of Dermatology
;
: 119-126, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-196199
ABSTRACT
BACKGROUND:
Chronic spontaneous urticaria (CSU) is considered a different disease entity from acute urticaria in relation to its pathogenesis, despite both disease types having similar clinical manifestations that include wheals, flares, and angioedema.OBJECTIVE:
We sought to identify the clinical factors that might predict the disease course of new-onset urticaria, determine whether the disease will be limited to an acute course or if it will progress to a chronic course, and to estimate the chronic progression rate in relation to the presence of each clinical factor and laboratory abnormality.METHODS:
We retrospectively reviewed the medical records of 348 patients with new-onset urticaria. Of these, 141 patients had progressed to chronic disease and 207 patients showed a limited to acute course with disease durations of less than 6 weeks. We compared the progressed to chronic and limited to acute disease groups in relation to differences in their clinical presentations and severities, and the laboratory data.RESULTS:
The overall chronic progression rate of new-onset urticaria was 40.5%. The chronic progression rate was highest in patients aged 30~39 years (52.3%), in patients prescribed antihistamines (52.9%), and when the cause of urticaria was unknown (51.8%). The laboratory test results did not differ significantly between the study groups.CONCLUSION:
Patients with new-onset urticaria are likely to have chronic courses when they are aged 30~39 years, when they have mild clinical symptoms initially, and when the cause of urticaria is difficult to identify.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Urticária
/
Prontuários Médicos
/
Doença Aguda
/
Doença Crônica
/
Estudos Retrospectivos
/
Progressão da Doença
/
Antagonistas dos Receptores Histamínicos
/
Angioedema
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Dermatology
Ano de publicação:
2015
Tipo de documento:
Artigo
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