Cytomegalovirus Retinitis after Intravitreal Bevacizumab Injection in an Immunocompetent Patient
Korean Journal of Ophthalmology
;
: 61-63, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-19703
ABSTRACT
We report a case of cytomegalovirus (CMV) retinitis after intravitreal bevacizumab injection. A 61-year-old woman with diabetic macular edema developed dense vitritis and necrotizing retinitis 3 weeks after intravitreal bevacizumab injection. A diagnostic vitrectomy was performed. The undiluted vitreous sample acquired by vitrectomy was analyzed by polymerase chain reaction and culture. Polymerase chain reaction of the vitreous was positive for CMV DNA. Other laboratory results did not show evidence of other infectious retinitis and systemic immune dysfunction. Human immunodeficiency virus antibodies were also negative. After systemic administration of ganciclovir, retinitis has resolved and there has been no recurrence of retinitis during the follow-up period of 12 months. Ophthalmologists should be aware of potential risk for CMV retinitis after intravitreal bevacizumab injection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
DNA Viral
/
Edema Macular
/
Reação em Cadeia da Polimerase
/
Retinite por Citomegalovirus
/
Inibidores da Angiogênese
/
Citomegalovirus
/
Fator A de Crescimento do Endotélio Vascular
/
Diagnóstico Diferencial
/
Injeções Intravítreas
/
Anticorpos Monoclonais Humanizados
Tipo de estudo:
Estudo diagnóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
2013
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS