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A Case of Thrombotic Thrombocytopenic Purpura Associated with Ticlopidine
Journal of the Korean Neurological Association ; : 512-514, 2000.
Artigo em Coreano | WPRIM | ID: wpr-197458
ABSTRACT
Ticlopidine, a widely used antiplatelet agent, has been rarely reported to cause thrombotic thrombocytopenic purpura (TTP). To the best of our knowledge, its occurrence has never before been reported in Korea. A 69 years old female patient suffered from an acute ischemic stroke. Ticlopidine 250mg bid was started and she followed an uneventful clin-ical course. The platelet count was normal on the 1st and the 12th day of ticlopidine administration. Around the 31st day, at home, she developed purpura, dyspnea and a stuporous mental status. Under the diagnosis of TTP, a plasma exchange was performed and her condition eventually returned to the baseline status. Ticlopidine induced TTP can developed abruptly despite close monitoring of platelet count, as illustrated by this case. Physicians prescribing ticlopi-dine should be aware of this potentially dangerous complication.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Troca Plasmática / Contagem de Plaquetas / Púrpura / Púrpura Trombocitopênica Trombótica / Ticlopidina / Acidente Vascular Cerebral / Diagnóstico / Dispneia / Estupor / Coreia (Geográfico) Tipo de estudo: Estudo diagnóstico Limite: Idoso / Feminino / Humanos País/Região como assunto: Ásia Idioma: Coreano Revista: Journal of the Korean Neurological Association Ano de publicação: 2000 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Troca Plasmática / Contagem de Plaquetas / Púrpura / Púrpura Trombocitopênica Trombótica / Ticlopidina / Acidente Vascular Cerebral / Diagnóstico / Dispneia / Estupor / Coreia (Geográfico) Tipo de estudo: Estudo diagnóstico Limite: Idoso / Feminino / Humanos País/Região como assunto: Ásia Idioma: Coreano Revista: Journal of the Korean Neurological Association Ano de publicação: 2000 Tipo de documento: Artigo