The Efficacy of Vaccinium Uliginosum for Early Age-Related Macula Degeneration
Journal of the Korean Ophthalmological Society
;
: 1255-1260, 2013.
Artigo
em Coreano
| WPRIM
| ID: wpr-197750
ABSTRACT
PURPOSE:
To evaluate the effect of Bog Bilberry (Vaccinium uliginosum) extract in eyes with early age-related macular degeneration (AMD).METHODS:
Forty-four eyes of forty four patients with early AMD were included in this randomized, double-blinded, and placebo-controlled study. All participants were randomly assigned to either the placebo group (n = 24), or the bog bilberry extract group (n = 20). Before drug administration, an ophthalmic examination which included slit lamp microscopy, best corrected visual acuity, and intraocular pressure was performed, and repeated 1and 3 months after treatment. Objective scatter index, glare and tear film break-up time were checked by Optical Quality Analysis System (OQAS, Visiometrics, Spain) and drusen volume, central macular thickness, and RPE and IS/OS junction thickness were investigated with spectral-domain optical coherence tomography (Spectralis, Heidelberg, Germany).RESULTS:
In the bog bilberry extract group, RPE and IS/OS junction thickness was significantly increased compared to the placebo group after 3 months of drug administration.CONCLUSIONS:
Bog Bilberry extract may play a favorable role in preventing the atrophic change of RPE and IS/OS junction layer and the progression of early macular degeneration.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Lágrimas
/
Acuidade Visual
/
Ofuscação
/
Vaccinium
/
Vaccinium myrtillus
/
Tomografia de Coerência Óptica
/
Áreas Alagadas
/
Olho
/
Pressão Intraocular
/
Degeneração Macular
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2013
Tipo de documento:
Artigo
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