A case of remitting seronegative symmetrical synovitis with pitting edema / 대한내과학회지

ABSTRACT

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare form of seronegative polyarthritis which is characterized by sudden onset of a symmetrical and peripheral polysynovitis, prominent pitting edema of both hands in elderly patient. It has a benign course and remits completely after steroid treatment. We describe a 77-year-old Korean man of RS3PE syndrome He presented with sudden onset polyarthritis and pitting edema of the dorsum of both hands and both feet. Rheumatoid factor was negative and erythrocyte sedimentation rate was high. Bone scintigraphy showed increased uptake in both wrist, knee, and ankle joints. His synovitis and pitting edema completely disappeared after steroid treatment.