Metronidazole Resistance and the Eradication of Helicobacter pylori / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 847-852, 1998.
Artigo
em Coreano
| WPRIM
| ID: wpr-198488
ABSTRACT
BACKGROUND/AIMS:
The success of Helicobacter pylori eradication is limited by antibiotic resistances, and the primary resistance to metranidazole seems to be high. In this study, the frequency af metronidazole resistance and the eradication rate in metronidazole-resistant H. pylori strain was evaluated.METHODS:
Sixty-eight patients were tested for metronidazole resistance using microdilution broth, the E test and disk diffusion method. Twenty-two patients were treated for 14 days with amoxicilline 2000 mg, metronidazole 750 mg, and tripotassium dicitrate bismuth 1200 mg.RESULTS:
Metronida-zole resistance was 46% (31/68). The eradication rates for H. pylori was 91.7% in patients with metronidazole-sensistive strains and 70% in patients with metronidazole-resistant strains.CONCLUSIONS:
Metronidazole resistance was high (46%) in Korea, however, triple therapy was an efficient method of eradicating H. pylori in both metronidazole sensitive and resistant strains.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera Péptica
/
Bismuto
/
Helicobacter pylori
/
Helicobacter
/
Difusão
/
Amoxicilina
/
Coreia (Geográfico)
/
Metronidazol
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Korean Journal of Gastrointestinal Endoscopy
Ano de publicação:
1998
Tipo de documento:
Artigo
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