Clinical Usefulness between High Dose Radioiodine Therapy and Helicobacter Pylori Infection after Total Thyroidectomy due to Well Differentiated Thyroid Cancer / 핵의학분자영상
Nuclear Medicine and Molecular Imaging
;
: 572-576, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-198897
ABSTRACT
PURPOSE:
Helicobacter (H) pylori infection has been considered the most important cause of gastritis, dyspepsia, and gastroduodenal ulcer. Radioiodine can be accumulated in the remaining thyroid tissue, salivary gland, and stomach. We investigated if the high radiation induced by radioiodine in the stomach after high dose radioiodine therapy (HD-RIT) is effective in the eradication of H. pylori infection. MATERIALS ANDMETHODS:
One hundred ninety nine patients (MF=33166, age 46.7+/-12.3 years) who had HD-RIT (dose 159.1+/-25.9 mCi, range 120-250 mCi) after thyroidectomy due to well differentiated thyroid cancer were enrolled. To detect H. pylori infection, the urea breath tests (UBT) were performed at 1 hour before HD-RIT and at 4 weeks after HD-RIT. The results of UBT were classified as positive (> or =50 dpm) or negative (<50 dpm), and analyzed its values.RESULTS:
Of 199 patients, 103 (51.8%) patients had positive UBT before HD-RIT. Of these, 80 patients had follow-up UBT after HD-RIT. Among them, 76 (95.0%) patients had persistent positive UBT and only 4 (5.0%) patients were changed negative UBT. Among 76 patients with persistent positive UBT, 26 (34.2%) patients had increased the values of follow-up UBT, 49 (64.5%) had decreased them, and 1 (1.3%) had shown the same value. The different values of UBT between before and after HD-RIT were 62+/-66.1 dpm in increased one of follow-up UBT, and 153.3+/-157.1 dpm in decreased one of follow-up UBT.CONCLUSION:
We conclude that the radiation induced by HD-RIT is ineffective in the eradication of H. pylori infection. However, it could be influential the degree or distribution of H. pylori infection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera Péptica
/
Glândulas Salivares
/
Estômago
/
Glândula Tireoide
/
Tireoidectomia
/
Ureia
/
Testes Respiratórios
/
Neoplasias da Glândula Tireoide
/
Seguimentos
/
Helicobacter pylori
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Nuclear Medicine and Molecular Imaging
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS