Acute Monocular Ophthalmoplegia Associated with Anti-GQ1b IgG Antibody

ABSTRACT

Some authors found the anti-GQ1b IgG antibody in some of their patients with acute postinfectious ophthalmoparesis without ataxia, "atypical MFS" or "acute ophthalmoparesis (AO)". Antecedent illness, acute ophthalmoparesis, CSF albuminocytologic dissociation, and the anti-GQ1b IgG antibody are useful markers for diagnosing AO. AO can be considered a variant or atypical form of MFS. We report two monocular AO patients who had the anti-GQ1b IgG antibody along with a literature review.