Pathological Complete Remission of Advanced Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombosis by Hepatic Arterial Infusion Chemotherapy
Gut and Liver
; : 266-269, 2010.
Article
em En
| WPRIM
| ID: wpr-199718
Biblioteca responsável:
WPRO
ABSTRACT
Cures for advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) are rare and difficult. We report a case of pathologically confirmed complete remission of HCC induced by hepatic arterial infusion chemotherapy (HAIC). A 45-year-old male patient had a massive HCC in the right lobe of the liver and tumor thrombus in the right and main portal veins. He achieved a partial response after two cycles of HAIC with 5-fluorouracil (750 mg/m2) and cisplatin (25 mg/m2). After the completion of six cycles he received a curative partial hepatectomy, and histopathology revealed complete necrosis without any viable tumor cell. He was in good health at a 4-month follow-up. These results suggest that this regimen is a promising therapeutic modality for the treatment of advanced HCC with PVTT.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Veia Porta
/
Trombose
/
Seguimentos
/
Cisplatino
/
Carcinoma Hepatocelular
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Fluoruracila
/
Hepatectomia
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Fígado
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Necrose
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
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Male
Idioma:
En
Revista:
Gut and Liver
Ano de publicação:
2010
Tipo de documento:
Article